publications | Eric A. Dunipace

2022

Optimal transport weights for causal inference

Eric A. Dunipace

May 2022

arXiv Bib

Graph-Based Tests for Multivariate Covariate Balance Under Multi-Valued Treatments

Eric A. Dunipace

Jul 2022

arXiv Bib

@article{dunipace_graph_2022,
  title = {Graph-Based Tests for Multivariate Covariate Balance Under Multi-Valued Treatments},
  author = {Dunipace, Eric A.},
  year = {2022},
  month = jul,
  day = {22},
}

Association Between Periodontal Disease and Cardiovascular Disease Using Publicly Available Data from the National Health and Nutrition Examination Survey (NHANES)

Kyari Sumayin Ngamdu, Indika Mallawaarachchi, Eric A. Dunipace, and 5 more authors

The American Journal of Cardiology, Jul 2022

Bib

@article{ngamdu_association_2022,
  title = {Association Between Periodontal Disease and Cardiovascular Disease Using Publicly Available Data from the National Health and Nutrition Examination Survey ({NHANES})},
  journal = {The American Journal of Cardiology},
  author = {Ngamdu, Kyari Sumayin and Mallawaarachchi, Indika and Dunipace, Eric A. and Chuang, Lin-Hsin and Jafri, S. Hammad and Shah, Nishant R. and Jeong, Youjin N. and Morrison, Alan R},
  year = {2022}
}

2021

Interpretable Model Summaries Using the Wasserstein Distance

Eric A. Dunipace, and Lorenzo Trippa

Dec 2021

arXiv Bib

@article{Dunipace2020,
  title = {Interpretable Model Summaries Using the Wasserstein Distance},
  pages = {1--42},
  author = {Dunipace, Eric A. and Trippa, Lorenzo},
  year = {2021},
  month = dec,
  day = {17}
}

2018

Liver Disease as a Predictor of New Onset Atrial Fibrillation

William A Huang, Eric A Dunipace, Julie M Sorg, and 1 more author

Journal of the American Heart Association, Dec 2018

Bib

@article{608465,
  title = {Liver Disease as a Predictor of New Onset Atrial Fibrillation},
  volume = {7},
  url = {https://www.ahajournals.org/doi/10.1161/JAHA.118.008703},
  number = {15},
  journal = {Journal of the American Heart Association},
  author = {Huang, William A and Dunipace, Eric A and Sorg, Julie M and Vaseghi, Marmar},
  year = {2018}
}

2014

TraumaLink: Helping People Survive Traffic Accidents in Bangladesh

Jon Moussally, Eric Dunipace, and Ryan Fu

In Health and South Asia, Cambridge, Massachusetts, Dec 2014

Bib

@incollection{Moussally2014,
  location = {Cambridge, Massachusetts},
  title = {{TraumaLink}: Helping People Survive Traffic Accidents in {B}angladesh},
  pages = {67--70},
  booktitle = {Health and {S}outh {A}sia},
  publisher = {The Lakshmi Mittal South Asia Institute at Harvard University},
  author = {Moussally, Jon and Dunipace, Eric and Fu, Ryan},
  year = {2014}
}

2011

Differential requirements for NAIP5 in activation of the NLRC4 inflammasome

K.L. Lightfield, J. Persson, N.J. Trinidad, and 7 more authors

Infection and Immunity, Dec 2011

Abs DOI Bib

Inflammasomes are cytosolic multiprotein complexes that assemble in response to infectious or noxious stimuli and activate the CASPASE-1 protease. The inflammasome containing the nucleotide binding domainleucine-rich repeat (NBD-LRR) protein NLRC4 (interleukin-converting enzyme protease-activating factor [IPAF]) responds to the cytosolic presence of bacterial proteins such as flagellin or the inner rod component of bacterial type III secretion systems (e.g., Salmonella PrgJ). In some instances, such as infection with Legionella pneumophila, the activation of the NLRC4 inflammasome requires the presence of a second NBDLRR protein, NAIP5. NAIP5 also is required for NLRC4 activation by the minimal C-terminal flagellin peptide, which is sufficient to activate NLRC4. However, NLRC4 activation is not always dependent upon NAIP5. In this report, we define the molecular requirements for NAIP5 in the activation of the NLRC4 inflammasome. We demonstrate that the N terminus of flagellin can relieve the requirement for NAIP5 during the activation of the NLRC4 inflammasome. We also demonstrate that NLRC4 responds to the Salmonella protein PrgJ independently of NAIP5. Our results indicate that NAIP5 regulates the apparent specificity of the NLRC4 inflammasome for distinct bacterial ligands. © 2011, American Society for Microbiology.
@article{Lightfield2011, title = {Differential requirements for {NAIP}5 in activation of the {NLRC}4 inflammasome}, volume = {79}, issn = {00199567}, doi = {10.1128/IAI.01187-10}, number = {4}, journal = {Infection and Immunity}, author = {Lightfield, K.L. and Persson, J. and Trinidad, N.J. and Brubaker, S.W. and Kofoed, E.M. and Sauer, J.-D. and Dunipace, Eric A. and Warren, S.E. and Miao, E.A. and Vance, R.E.}, year = {2011} }

2008

Critical function for Naip5 in inflammasome activation by a conserved carboxy-terminal domain of flagellin

K.L. Lightfield, J. Persson, S.W. Brubaker, and 10 more authors

Dec 2008

Abs DOI Bib

Inflammasomes are cytosolic multiprotein complexes that sense microbial infection and trigger cytokine production and cell death. However, the molecular components of inflammasomes and what they sense remain poorly defined. Here we demonstrate that 35 amino acids of the carboxyl terminus of flagellin triggered inflammasome activation in the absence of bacterial contaminants or secretion systems. To further elucidate the host flagellin-sensing pathway, we generated mice deficient in the intracellular sensor Naip5. These mice failed to activate the inflammasome in response to the 35 amino acids of flagellin or in response to Legionella pneumophila infection. Our data clarify the molecular basis for the cytosolic response to flagellin.
@article{Lightfield2008, title = {Critical function for {Naip5} in inflammasome activation by a conserved carboxy-terminal domain of flagellin}, volume = {9}, issn = {15292908}, doi = {10.1038/ni.1646}, number = {10}, journaltitle = {Nature Immunology}, author = {Lightfield, K.L. and Persson, J. and Brubaker, S.W. and Witte, C.E. and von Moltke, J. and Dunipace, Eric A. and Henry, T. and Sun, Y.-H. and Cado, D. and Dietrich, W.F. and Monack, D.M. and Tsolis, R.M. and Vance, R.E.}, year = {2008} }